Is eating Edible Bird Nest during pregnancy well?

During pregnancy, pregnant women are the most “toned”. Among dishes that are soaked for mother’s choice, the nest is regarded as indispensable food during this time. So, the Edible Bird Nest is really good for pregnant women? Should pregnant women eat Edible Bird Nest? And the nest has the benefits that people need so. Let’s get to know each other.

1. Do you eat Edible Bird Nest when pregnant

Nest soup is very suitable for pregnant women to eat, to ensure their health as well as future for the baby healthier, smarter you should choose these Edible Bird Nest brand:http://www.top10besttips.com/top-10-best-stores-edible-birds-nest-soup-in-u-s-a-with-high-quality-good-price.html. Many studies have shown that pregnant women eat nourishment not only to nourish their mother but also to make the baby healthier, smarter and better prevent disease. For postpartum women, reduce fatigue, fast recovery and health, Edible Bird Nest is probably the most nutritious natural food for mother and baby at this stage.

Is eating Edible Bird Nest during pregnancy well?

2. What are the benefits of eating nest during pregnancy?

Many patients and pregnant women want nutritional supplements by eating nests, in fact, there are many benefits for pregnant women when eating Edible Bird Nest, not only nutritional supplement it also helps to. fetal development.
To provide the nutrients and supplements needed during pregnancy
Women who are pregnant during the first trimester often get very little food, and the supply and absorption of nutrients is greatly affected. Only 1 – 2 tablespoons of skins per day can provide nutrition for pregnant women with a nutritious meal.
Supplements the fetal amino acids from the nest
The first three months of pregnancy, this is the most important stage, the nervous system of the fetus and organs in the body are formed and developed, the nest contains up to 10% of the amino acids necessary for the the development of the fetus, increase the immunity of the body, increase the development of the nervous system, improve memory.
To prevent stretch marks
About 70 to 90% of women in their first pregnancy, when their abdomen grows too fast, will cause collagen fibers and fibrous tissue to grow out of the abdominal cavity. It usually appears in the lower abdomen, thighs, buttocks, or chest areas, which may appear as purple or chestnut stripes, which, when present, are difficult to remove. Nest nests contain a peptide element – EGF, called “beauty”. It can stimulate and promote cell division, colalagen production, quick repair of damaged skin, prevent stretch marks and help skin become more elastic and smooth.
Prevention of miscarriage
Pregnant women using Edible Bird Nest effectively can improve immunity, reduce the possibility of disease leading to unwanted pregnancy. There are many benefits of eating nest during pregnancy, but pregnant women should also note that due to the nest is expensive so it is best to make allowances according to economic conditions allowed by the family.

Characterization of Edible Bird Nest by peptide fingerprinting with principal component analysis

Edible Bird Nest, or cubilose, is a health food supplement originated from salivary secretion by specific swiftlets, mainly from Aerodramus fuciphagus and Aerodramus maximus (Kang et al., 1991), which has been proven to have nutritious and therapeutic values, such as anti-influenza viruses, antioxidant, skin lightening, bone strength improvement, anti-inflammatory, and epidermal growth enhancement (Kong et al., 1987; Kong et al., 1989; Guo et al., 2006; Aswir and Wan Nazaimoon, 2011; Matsukawa et al., 2011; Yew et al., 2014; Chan et al., 2015). Southeast Asian countries, including Indonesia, Malaysia, Vietnam, and Thailand, are the major exporting countries of Edible Bird Nest. Human consumption and medicinal application of Edible Bird Nest could be dated back to the Tang dynasty (618–907 A.D.) and the Sung dynasty (960–1279 A.D.) in China (Koon and Cranbrook, 2002).

OBJECTIVES

Proteins are the major component and play a key role in nutritious and therapeutic functions of Edible Bird Nest; however, limited studies have been conducted on the protein due to difficulties in extraction, isolation as well as identification. This study aimed to provide comprehensive information for the quality evaluation of Edible Bird Nest peptides, which would be a valuable reference for further study on Edible Bird Nest proteins.

METHODS

Here, we developed a quality control method using high performance liquid chromatography (HPLC) peptide fingerprints deriving from Edible Bird Nest being digested with simulated gastric fluid. The characteristic peptide peaks were collected and identified by LC-MS/MS.

RESULTS

The characteristic peptide peaks, corresponding to the protein fragments of acidic mammalian chitinase-like, lysyl oxidase, and Mucin-5AC-like, were identified and quantified. Interestingly, the principal component analysis indicated that the fingerprints were able to discriminate colour of Edible Bird Nest (white/red) and production sites (cave/house) of White Edible Bird Nest on the same weight basis. As proposed by the model developed in this study, Muc-5AC-like and AMCase-like proteins were the markers with the highest discriminative power.

CONCLUSIONS

The overall findings suggest that HPLC peptide fingerprints were able to clearly demonstrate peptide profile differences between genuine and adulterated Edible Bird Nest samples; and classify Edible Bird Nest samples by its color and production site. In addition, the protein identification results suggested that Muc-5AC-like protein was the major protein in Edible Bird Nest.

Introduction

Edible Bird Nest, or cubilose, is a health food supplement originated from salivary secretion by specific swiftlets, mainly from Aerodramus fuciphagus and Aerodramus maximus (Kang et al., 1991), which has been proven to have nutritious and therapeutic values, such as anti-influenza viruses, antioxidant, skin lightening, bone strength improvement, anti-inflammatory, and epidermal growth enhancement (Kong et al., 1987; Kong et al., 1989; Guo et al., 2006; Aswir and Wan Nazaimoon, 2011; Matsukawa et al., 2011; Yew et al., 2014; Chan et al., 2015). Southeast Asian countries, including Indonesia, Malaysia, Vietnam, and Thailand, are the major exporting countries of Edible Bird Nest. Human consumption and medicinal application of Edible Bird Nest could be dated back to the Tang dynasty (618–907 A.D.) and the Sung dynasty (960–1279 A.D.) in China (Koon and Cranbrook, 2002).
Although Edible Bird Nest has been served as an esteemed food in Chinese community for over 1000 years, limited research has been conducted on Edible Bird Nest and its proteins. Protein is a major part of Edible Bird Nest accounting for 50% of Edible Bird Nest dried weight on average (Jiangsu New Medicine College, 1977); it is conjectured to be a key factor of its nourishing and/or medicinal functions. The epidermal growth factor (EGF)-like peptide was partially purified with Bio-Gel P-10 columns from aqueous extracts of Edible Bird Nest that stimulated cell division and growth and enhanced tissue growth and regeneration (Kong et al., 1987; Kong et al., 1989). Two major bands (~106 kDa and ~128 kDa) were identified by sodium dodecyl sulfate–polyacrylamide gel electrophoresis (SDS–PAGE) as ‘sialo-glycoprotein’. Nevertheless, no satisfactory result was obtained from protein identification studies that include N-terminal sequence determination (Edman degradation), matrix-assisted laser desorption ionization–tandem time of flight (MALDI–TOF/TOF), and liquid chromatography–tandem mass spectrometry (LC–MS/MS) (Zhang et al., 2012). Acidic mammalian chitinase-like (AMCase-like) protein fragments from Meleagris gallopavo and an allergen homologous to ovo-inhibitor have been identified by 2-DE assays followed by MALDI–TOF/TOF/MS analysis in Edible Bird Nest extract (Liu et al., 2012). In addition, a microbial nitrate reductase, converting nitrate to nitrite and playing a role in the colour change of White and Red Edible Bird Nest, was identified by mass spectroscopy (Chan et al., 2013b). Nonetheless, it remains unclear whether those identified proteins could accurately represent the majority of Edible Bird Nest protein. The difficulties encountered in research of Edible Bird Nest proteins are: (i) extracting and purifying proteins; and (ii) lacking of full Aerodramus genome sequence.
Owing to the limited supply and labour-intensive cleaning process, Edible Bird Nest is always expensive with current prices ranging from USD 500 to 15000/kg. Driven by the lucrative return, various materials, including Tremella fungus, fried porcine skin, carrageenan, agar, and gelatin, which are almost indistinguishable from the genuine samples by visual inspection, were commonly adulterated into Edible Bird Nest in order to increase the net weight (Ma and Liu, 2012). Some businesses have been known to mix low-quality Edible Bird Nest into high-quality Edible Bird Nest and selling that at a high price. Occasionally, consumers have been counterfeited into purchasing lower priced house Edible Bird Nest at a premium price associated with cave Edible Bird Nest. About 40 publications are found in PubMed today, and nearly one-third of the publications are published in the last 5 years. Besides, most of the publications still retained in elucidating chemical composition as the quality control parameters: since no official method has been established for quality surveillance of Edible Bird Nest (Deng et al., 2006; Wang et al., 2006; Wu et al., 2010; Chan et al., 2013a).
Here, we attempt to find a key to open these proteome barriers by high performance liquid chromatography (HPLC) peptide fingerprinting. HPLC fingerprinting is one promising tool widely used in the modern standardization of herbal extracts (Department of Health, Hong Kong, 2010; Chinese Pharmacopoeia Commission, China, 2015), which could be applied to Edible Bird Nest as a robust technique in qualitative and quantitative controls. Firstly, an over-stewing method was developed to extract most of the Edible Bird Nest protein. Secondly, simulated gastric fluid (SGF) was used to digest Edible Bird Nest protein fully into peptides that can be separated by HPLC according to their polarity. Thirdly, according to the most relevant NCBI protein database, the characteristic peaks in chromatograms were identified and quantified. In addition, principal component analysis (PCA) and hierarchical cluster analysis (HCA) were adopted to reveal the relationships of factors within the data, including colour, country of origin, and production site of Edible Bird Nest. The results therefore contributed to the authentication and classification of Edible Bird Nest. This study aimed to provide comprehensive information for the quality evaluation of Edible Bird Nest protein at the peptide level, which would be a valuable reference for further study on Edible Bird Nest proteins